My research interests include bone mechanics, passive microfluidics, cell mechanics, cancer metastasis and laser processing.
Bone Mechanics
Bone mechanics is the study of the mechanical properties and behavior of bones under various loads and stresses. It investigates how bones resist deformation, maintain strength, and adapt to mechanical forces. This field combines biomechanics, material science, and physiology to understand bone structure, fracture mechanics, and remodeling processes. Applications include orthopedic implant design and treatments for osteoporosis.
Passive Microfluidics
Passive microfluidics focuses on controlling the flow and behavior of fluids in microchannels without external forces like pumps or electric fields. It relies on capillary action, gravity, surface tension, and channel geometry for fluid manipulation. Passive microfluidic devices are cost-effective and energy-efficient, often used in lab-on-a-chip systems for applications such as diagnostics, chemical analysis, and environmental monitoring.
Cell Mechanics
Cell mechanics studies the mechanical properties and responses of cells, including their stiffness, adhesion, and deformation under external forces. It plays a crucial role in understanding cellular functions such as migration, division, and differentiation. Insights into cell mechanics are essential for research on disease progression, particularly in cancer, where changes in mechanical properties can indicate metastasis.
Cancer Metastasis
Cancer metastasis is the process by which cancer cells spread from the primary tumor to distant parts of the body, forming secondary tumors. This involves detachment from the tumor, invasion into surrounding tissues, entry into the bloodstream or lymphatic system, and colonization at a new site. Metastasis is a leading cause of cancer mortality, and its study integrates cell biology, genetics, and biomechanics.
Laser Processing
Laser processing involves using high-intensity laser beams to modify materials through cutting, welding, engraving, micromachining, or surface treatment. It is widely used in industries due to its precision, non-contact nature, and ability to work with diverse materials. Applications include microfabrication for electronics, medical devices, and advanced manufacturing techniques like femtosecond laser micromachining.