环境与化学工程学院

汤少恒，教授，硕导，2014年博士毕业于厦门大学，同年进入美国得克萨斯大学从事博士后研究，2022年入职江苏科技大学，并入选江苏省特聘教授。本人长期从事功能性纳米材料的合成制备，及其在生物医学领域的前沿应用和相关机理的研究。至今已在Angew. Chem. Int. Ed., Adv. Funct. Mater, Small,Chem. Comm., Nano Res.等国际学术期刊上发表论文24篇，累计被引用超过 5600 次，h-index 21(Google Scholar)。至今共主持或参与美国联邦 NIH 基金项目 1 项及得州CPRIT 基金项目 2 项，总计科研经费 315 万美元。并参与申请多项国际及国内专利，其中 6 项专利已获授权。

1. 有机高分子荧光探针的设计与合成，并将其应用于针对肾脏原发肿瘤及转移瘤的原位成像及造影。

2. 肾脏可清除纳米颗粒的设计与合成，并将其应用于针对急性肾损伤（AKI）和慢性肾病（CKD）的早期诊断和靶向治疗。

3. RNA 药物递送系统的设计与合成，并积极探索其在疫苗、遗传疾病以及抗癌治疗等方面的前沿应用和临床转换。

4. 高分子放疗药物的开发与合成。

代表论文：

1. Chengpeng Hao, Kefa Hu, Jingcong Xie, Xinyi Tong, Xiaomeng Zhang, Zhipeng Qi*, Shaoheng Tang*. "Recent Advancements in the Biomanufacturing of Crocetin and Crocins: Key Enzymes and Metabolic Engineering" J. Agric. Food Chem. 2025. 11. 6400

2. Hai Huang, Xinrong Zhu, Chengpeng Hao, Weizhang Xu, Shasha Sun*, Hongzhou Cai*, Shaoheng Tang*. "Non-invasive diagnosis of acute kidney injury using ZW800-1-PEG in vivo fluorescence imaging" J. Mol. Struct. 2025. 2. 143516

Pre-JUST

1. Shaoheng Tang, Yingyu Huang and Jie Zheng. “Salivary Excretion of Renal‐Clearable Silver Nanoparticles” Angew. Chem. Int. Ed. (Highlighted as Hot Paper) 2020, 45, 19894

2. Shaoheng Tang and Jie Zheng. “Antibacterial Activity of Silver Nanoparticles: Structural Effects” Adv. Healthcare Mater.( ESI Highly Cited Paper). 2018, 7, 1701503

3. Shaoheng Tang, Chuanqi Peng, Jing Xu, Bujie Du, Qingxiao Wang, Rodrigo D Vinluan III, Mengxiao Yu, Moon J Kim, Jie Zheng. “Tailoring Renal Clearance and Tumor Targeting of Ultrasmall Metal Nanoparticles with Particle Density”, Angew. Chem. Int. Ed. (Highlighted as VIP) 2016, 55, 16039

4. Shaoheng Tang, Mei Chen and Nanfeng Zheng, “Multifunctional Ultrasmall Pd Nanosheets for Enhanced Near-infrared Photothermal Therapy and Chemotherapy of Cancer”. Nano Res.. 2015, 1, 165

5. Shaoheng Tang, Mei Chen and Nanfeng Zheng, “Sub-10-nm Pd Nanosheets with Rena Clearance for Efficient Near-Infrared Photothermal Cancer Therapy”. Small. 2014. 15, 3139.

6. Shaoheng Tang, Xiaoqing Huang and Nanfeng Zheng, “Silica Coating Improves the Efficacy of Pd Nanosheets for Photothermal Therapy of Cancer Cells Using Near Infrared Laser”, Chem. Comm.. 2011, 47, 3948.

7. Shaoheng Tang, Xiaoqing Huang, Xiaolan Chen, Nanfeng Zheng. “Hollow Mesoporous Zirconia Nanocapsules for Drug Delivery”, Adv. Funct. Mater.. 2010, 20, 2442

8. Xiaoqing Huang, Shaoheng Tang, Xiaoliang Mu, Yan Dai, Guangxu Chen, Zhiyou Zhou, Fangxiong Ruan, Zhilin Yang, Nanfeng Zheng. “Freestanding Palladium Nanosheets with Plasmonic and Catalytic Properties”,Nature nanotechnology. 2011, 6, 28.

9. Xiaoqing Huang, Shaoheng Tang, Jing Yang, Yueming Tan, Nanfeng Zheng. “Etching Growth Under Surface Confinement: An Effective Strategy to Prepare Mesocrystalline Pd Nanocorolla”, J. Am. Chem. Soc. 2011, 133, 15946

10. Xiaoqing Huang, Shaoheng Tang, Huihui Zhang, Zhiyou Zhou, Nanfeng Zheng. “Controlled Formation of Concave Tetrahedral/Trigonal Bipyramidal Palladium Nanocrystals”, J. Am. Chem. Soc. 2009, 39, 13916.