1. 有机高分子荧光探针的设计与合成，并将其应用于针对肾脏原发肿瘤及转移瘤的原位成像及造影。
2. 肾脏可清除纳米颗粒的设计与合成，并将其应用于针对急性肾损伤（AKI）和慢性肾病（CKD）的早期诊断和靶向治疗。
3. RNA 药物递送系统的设计与合成，并积极探索其在疫苗、遗传疾病以及抗癌治疗等方面的前沿应用和临床转换。
4. 高分子放疗药物的开发与合成。
代表论文：
1. Shaoheng Tang, Yingyu Huang and Jie Zheng. “Salivary Excretion of Renal‐Clearable Silver Nanoparticles” Angew. Chem. Int. Ed. (Highlighted as Hot Paper) 2020, 45, 19894
2. Shaoheng Tang and Jie Zheng. “Antibacterial Activity of Silver Nanoparticles: Structural Effects” Adv. Healthcare Mater.( ESI Highly Cited Paper). 2018, 7, 1701503
3. Shaoheng Tang, Chuanqi Peng, Jing Xu, Bujie Du, Qingxiao Wang, Rodrigo D Vinluan III, Mengxiao Yu,
Moon J Kim, Jie Zheng. “Tailoring Renal Clearance and Tumor Targeting of Ultrasmall Metal Nanoparticles
with Particle Density”, Angew. Chem. Int. Ed. (Highlighted as VIP) 2016, 55, 16039
4. Shaoheng Tang, Mei Chen and Nanfeng Zheng, “Multifunctional Ultrasmall Pd Nanosheets for Enhanced Near-infrared Photothermal Therapy and Chemotherapy of Cancer”. Nano Res.. 2015, 1, 165
5. Shaoheng Tang, Mei Chen and Nanfeng Zheng, “Sub-10-nm Pd Nanosheets with Rena Clearance for
Efficient Near-Infrared Photothermal Cancer Therapy”. Small. 2014. 15, 3139.
6. Shaoheng Tang, Xiaoqing Huang and Nanfeng Zheng, “Silica Coating Improves the Efficacy of Pd
Nanosheets for Photothermal Therapy of Cancer Cells Using Near Infrared Laser”, Chem. Comm.. 2011. 47, 3948.
7. Shaoheng Tang, Xiaoqing Huang, Xiaolan Chen, Nanfeng Zheng. “Hollow Mesoporous Zirconia
Nanocapsules for Drug Delivery”, Adv. Funct. Mater.. 2010, 20, 2442
8. Xiaoqing Huang, Shaoheng Tang, Xiaoliang Mu, Yan Dai, Guangxu Chen, Zhiyou Zhou, Fangxiong Ruan,
Zhilin Yang, Nanfeng Zheng. “Freestanding Palladium Nanosheets with Plasmonic and Catalytic Properties”,Nature nanotechnology. 2011, 6, 28.
9. Xiaoqing Huang, Shaoheng Tang, Jing Yang, Yueming Tan, Nanfeng Zheng. “Etching Growth Under
Surface Confinement: An Effective Strategy to Prepare Mesocrystalline Pd Nanocorolla”, J. Am. Chem. Soc.
2011, 133, 15946
10. Xiaoqing Huang, Shaoheng Tang, Huihui Zhang, Zhiyou Zhou, Nanfeng Zheng. “Controlled Formation of Concave Tetrahedral/Trigonal Bipyramidal Palladium Nanocrystals”, J. Am. Chem. Soc. 2009, 39, 13916.
