主持项目：

（1）2023-2025，智能核酸逻辑门控的3D脂肪肝多靶标传感监测研究，国家自然科学青年基金项目，主持 （在研）；

（2）2022-2025，核酸逻辑门控的脂肪肝多靶标传感监测及药物响应研究，江苏省自然科学基金青年基金，主持 （在研）；

（3）2022-2025，江苏科技大学人才启动基金，主持（在研）。

参与项目：

（1）2023-2026，DNA水凝胶对环境水样中抗生素抗性基因的光动力控温萃取研究，国家自然科学基金面上项目，参与

[1] 王丽娜；沈薇；莫檬嘉；唐盛；张景慧；曾学民；陈天瑜，一种磁性单滴微萃取荧光开关结合PDA涂层囊泡检测GST的方法，2021-11-19，中国，202111399405.3 （2023-11-授权）CN 114018892 B

[2] 陈文慧；邝敬宇；沈薇；张景慧；唐盛；李婷婷；姚瑶，由miRNA-211和H2S协同触发的3D DNA network结构及其制备方法和应用，2022-06-01, 中国，202210620605.5（2025-03-18授权）CN 114958968 A

[3] 唐盛；李婷婷；张景慧；沈薇；宋美旗；沈可；呼雅雪，甲基丙烯酰化透明质酸高分子复合材料及其制备方法和应用，2023-11-16, 中国，202311530450.7（2024-04-公开）CN117801135A

[4] 唐盛；吴俊雯；沈薇；张景慧；徐美凤；崔书华，碳纳米管在miRNAs检查及细胞成像中的应用，2024-07-20, 中国，202410976485.1（2024-11-公开）CN118931532A

[5] 沈薇；王丽娜；吴芳琪；庄曜；张景慧；唐盛；徐美凤；周雪艳，AIE荧光探针、制备方法及同时检测LNCaP细胞两种抗原的应用，2023-08-31, 中国，202311114153.4（2023-12-公开）CN 117233372 A

[6] 沈薇；吴芳琪；王丽娜；张景慧；唐盛；吴俊雯；李梦秋，基于核仁蛋白和胞内microRNA逻辑门控的体系、制备方法和应用，2023-08-31, 中国，202311114137.5（2023-12-公开）CN 117210536 A

[7] 沈薇；马紫玉；唐盛；宋畅；雷姿；张景慧，酶辅助链置换结合液相色谱法实现单核苷酸多态性精准指征的分析方法，2023-08-30, 中国，202311103143.0（2023-12-公开）CN 117230162 A

[8] 沈薇；曾学民；王丽娜；唐盛；张景慧；马紫玉；苗紫昀，人造细胞生物传感系统及其制备方法和应用，2022-09-30, 中国，202211211770.1（2023-06-公开）CN 116287228 A

[9] 沈薇；宋畅；马紫玉；姜依依；唐盛；刘畅；张景慧，基于液相色谱检测多种MicroRNA自生成可区分荧光探针的一锅法，2022-08-29, 中国，202211039822.1（2023-03-公开）CN 115873948 A

[10] 沈薇；王丽娜；曾学民；唐盛；张景慧；苗紫昀，智能手机APP结合DSN酶微流体芯片比色检测miRNA-21的方法，2022-08-29, 中国，202211039813.2（2023-03-公开）CN 115855920 A

[11] 邝敬宇；陈文慧；李婷婷；沈薇；唐盛；毛威；张景慧；侯伟林，由ATP和H2S协同触发的Ag NPs-DOX-DNA 水凝胶及其制备方法和应用，2022-08-11, 中国，202210962075.2（2023-04-公开）CN 115919744 A

2025年：

[11]Wu Junwen, Zeng Xuemin, Wang, Lina, Zhang Jinghui, Cui Shuhua, Ma Zixiao, Pan Ruirong, Liu Chang, Kong Dezhao, Song Juan, Liu Lei, Feng Chunying, Shen Wei, Suo Xiaocen, Lin Zixia, Lee Hian Kee*, Tang Sheng*, Embedding carbon nanotubes in artificial cells enhances probe transfer, Advanced Materials,  (2025) 2418271 (SCI 一区, IF: 27.4, Top期刊)

[10] Song Meiqi, Zhang Jinghui*, Shen Ke, Hu Yaxue, Shen Wei, Tang Sheng*, Lee Hian Kee*, Application of smart-responsive hydrogels in nucleic acid and nucleic acid-based target sensing: A review , Biosensors and Bioelectronics, 267 (2025) 116803 (SCI 一区, IF: 10.7, Top期刊)

2024年：

[9] Wang Lina, Zhuang Yao, Pan Ruirong, Wang Tingwei, Zhang Jinghui*, Wang Dongyang, Liu Chang, Shen Wei*, Tang Sheng*, Simultaneous targeting and monitoring of free antigen and in-situ membrane antigen in prostate cancer cells via an aggregation-induced emission bifunctional probe, Biosensors and Bioelectronics, 263 (2024) 116581 (SCI 一区, IF: 10.7, Top期刊)

[8] Li Yunxin, Zhang Jinghui*, Chen Jisen, Zhu Feng*, Liu Zhiqiang, Bao Peng, Shen Wei, Tang Sheng*, Detection of SARS-CoV-2 based on artificial intelligence-assisted smartphone: A review, Chinese Chemical Letters,  35 (2024) 109220 (SCI 一区, IF: 9.1, Top期刊)

[7] Ma Ziyu, Xu Junjie, Hou Weilin, Lei Zi, Li Tingting, Shen Wei*, Yu Hui*, Liu Chang, Zhang Jinghui, Tang Sheng*, Single Nucleotide Polymorphisms Detection of Circulating Tumor DNA by Strand Displacement Amplification Coupled with Liquid Chromatography, Analytical Chemistry, 96 (2024) 5195-5204 (SCI 一区, IF: 7.4, Top期刊)

[6] Hou Weilin, Mao Wei, Yu Dasong, Pan Yuquan, Shen Wei*, Zhang Jinghui, Kong Dezhao, Zang Linlin, Dai Hongliang, Yang Fu, Lee Hian Kee*, Tang Sheng*, Photo-crosslinked hydrogel as a sensing platform for sensitive detection of free bilirubin in urine samples , Sensors and Actuators B: Chemical, 411 (2024) 135663 (SCI 一区, IF: 8.4, Top期刊）

[5] Zeng Xuemin, Wang Lina, Liu Chang*, Zhang Jinghui, Shi Hai-Wei, Shen Wei*, Kong Dezhao, Huang Cheng, Lee Hian Kee, Tang Sheng*, An integrated liposome-based microfluidic strategy for rapid colorimetric analysis: A case study of microRNA-21 detection , Talanta, 272 (2024) 125838 (SCI 一区, IF: 6.1, Top期刊)

[4] Song Chang, Ma Ziyu, Zhang Mengyu, Liu Chang*, Tang Sheng*, Zhang Jinghui, Song Juan, Yu Hui, Lee Hian Kee, Shen Wei*, Multiplex detection of single nucleotide polymorphisms by liquid chromatography for non-small cell lung cancer staging, Analytical Chemistry, 96 (2024) 1054-1063 (SCI 一区, IF: 7.4, Top期刊)

2023年：

[3] Chen Wenhui, Li Tingting, Chen Chengbo, Zhang Jinghui, Ma Ziyu, Hou Weilin, Yao Yao, Mao Wei, Liu Chang, Kong Dezhao,Tang Sheng*, Shen Wei*, Three-dimensional ordered DNA network constructed by a biomarker pair for accurate monitoring of colorectal cancer, Biosensors and Bioelectronics, 232 (2023) 115335 (SCI 一区, IF: 12.545, Top期刊）

2022年：

[2] Wang Lina, Zhang Jinghui, Shen Wei*, Zeng Xuemin, Lee Hian Kee*,Tang Sheng*, Can direct-immersion aqueous-aqueous microextraction be achieved when using a single-drop system?Analytical Chemistry, 94 (2022) 12538-12545 (SCI 一区, IF: 8.008, Top期刊)

[1] Yao Yao, Hu Tao, Chai Yaqian, Ju Jiahe, Zhang Jinghui*, Shen Wei*, Shi Haiwei, Liu Chang, Huang Cheng, Tang Sheng*, A rapid cusp-covering to Au nanostar as plasmonic sensor in a single-drop microreactor for the determination of kanamycin in biosamples, Sensors and Actuators B: Chemical, 366 (2022) 131993 (SCI 一区, IF: 7.460, Top期刊）

2021年以前：

[1] Jinghui Zhang, Zongyang Qiu, Jiahui Fan, Fang He, Wenyuan Kang, Sihui Yang, Hong-Hui Wang*, Jing Huang*, Zhou Nie*, Scan and Unlock: A Programmable DNA Molecular Automaton for Cell-Selective Activation of Ligand-Based Signaling. Angewandte Chemie International Edition, 2021, 60(12), 6733-6743.

[2] Shanfang Hu¹, Jinghui Zhang¹, Rui Tang, Jiahui Fan, Huiqiong Liu, Wenyuan Kang, Chunyang Lei, Zhou Nie*, Yan Huang*, Shouzhuo Yao, Click-Type protein-DNA conjugation for Mn²⁺ imaging in living cells. Analytical Chemistry, 2019, 91(15), 10180-10187.

[3] Jinghui Zhang¹, Tai Sun¹, Aping Niu¹, Yu-Mei Tang, Shun Deng, Wei Luo, Qun Xu*, Dapeng Wei*, De-Sheng Pei*, Perturbation effect of reduced graphene oxide quantum dots (rGOQDs) on aryl hydrocarbon receptor (AhR) pathway in zebrafish. Biomaterials. 2017,133, 49-59.  

[4]  Miao Wang, Fang He, Hao Li, Sihui Yang, Jinghui Zhang, Pradipta Ghosh, Hong-Hui Wang*, Zhou Nie*. Near-Infrared Light-Activated DNA-Agonist Nanodevice for Nongenetically and Remotely Controlled Cellular Signaling and Behaviors in Live Animals. Nano Letter, 2019, 10; 19(4), 2603-2613.

[5] Hao Li, Miao Wang, Tianhui Shi, Sihui Yang, Jinghui Zhang, Hong-Hui Wang *, Zhou Nie *. A DNA-Mediated Chemically Induced Dimerization (D-CID) Nanodevice for Nongenetic Receptor Engineering To Control Cell Behavior. Angewandte Chemie International Edition, 2018, 6; 57(32):10226-10230.

[6] Shun Deng, Pan-Pan Jia, Jinghui Zhang, Muhammad Junaid, Aping Niu, Yan-Bo Ma, Ailing Fu*, De-Sheng Pei*, Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs), Journal of Hazardous Materials, 2018, 357, 146-158.

[7] Li Jing¹, Aping Niu¹, Chun-Jiao Lu, Jinghui Zhang, Muhammad Junaid, Phyllis R Strauss, Ping Xiao, Xiao Wang, Yi-Wei Ren*, De-Sheng Pei*. A novel forward osmosis system in landfill leachate treatment for removing polycyclic aromatic hydrocarbons and for direct fertigation. Chemosphere, 2017, 168, 112-121.

[8] Jinghui Zhang¹, Aping Niu¹, Jing Li, Jianwei Fu, Qun Xu*, De-Sheng Pei*. In vivo characterization of hair and skin derived carbon quantum dots with high quantum yield as long-term bioprobes in zebrafish. Scientific Reports, 2016, 6, 37860.

[9] Jianwei Fu, Zhonghui Chen, Minghuan Wang, Shujun Liu, Jinghui Zhang, Jianan Zhang, Runping Han, Qun Xu*. Adsorption of methylene blue by a high-efficiency adsorbent (polydopamine microspheres): Kinetics, isotherm, thermodynamics and mechanism analysis. Chemical Engineering Journal, 2015, 259, 53-61.

主持项目：

（1）2023-2025，智能核酸逻辑门控的3D脂肪肝多靶标传感监测研究，国家自然科学青年基金项目，主持 （在研）；

（2）2022-2025，核酸逻辑门控的脂肪肝多靶标传感监测及药物响应研究，江苏省自然科学基金青年基金，主持 （在研）；

（3）2022-2025，江苏科技大学人才启动基金，主持（在研）。

参与项目：

（1）2023-2026，DNA水凝胶对环境水样中抗生素抗性基因的光动力控温萃取研究，国家自然科学基金面上项目，参与

[1] 王丽娜；沈薇；莫檬嘉；唐盛；张景慧；曾学民；陈天瑜，一种磁性单滴微萃取荧光开关结合PDA涂层囊泡检测GST的方法，2021-11-19，中国，202111399405.3 （2023-11-授权）CN 114018892 B

[2] 陈文慧；邝敬宇；沈薇；张景慧；唐盛；李婷婷；姚瑶，由miRNA-211和H2S协同触发的3D DNA network结构及其制备方法和应用，2022-06-01, 中国，202210620605.5（2025-03-18授权）CN 114958968 A

[3] 唐盛；李婷婷；张景慧；沈薇；宋美旗；沈可；呼雅雪，甲基丙烯酰化透明质酸高分子复合材料及其制备方法和应用，2023-11-16, 中国，202311530450.7（2024-04-公开）CN117801135A

[4] 唐盛；吴俊雯；沈薇；张景慧；徐美凤；崔书华，碳纳米管在miRNAs检查及细胞成像中的应用，2024-07-20, 中国，202410976485.1（2024-11-公开）CN118931532A

[5] 沈薇；王丽娜；吴芳琪；庄曜；张景慧；唐盛；徐美凤；周雪艳，AIE荧光探针、制备方法及同时检测LNCaP细胞两种抗原的应用，2023-08-31, 中国，202311114153.4（2023-12-公开）CN 117233372 A

[6] 沈薇；吴芳琪；王丽娜；张景慧；唐盛；吴俊雯；李梦秋，基于核仁蛋白和胞内microRNA逻辑门控的体系、制备方法和应用，2023-08-31, 中国，202311114137.5（2023-12-公开）CN 117210536 A

[7] 沈薇；马紫玉；唐盛；宋畅；雷姿；张景慧，酶辅助链置换结合液相色谱法实现单核苷酸多态性精准指征的分析方法，2023-08-30, 中国，202311103143.0（2023-12-公开）CN 117230162 A

[8] 沈薇；曾学民；王丽娜；唐盛；张景慧；马紫玉；苗紫昀，人造细胞生物传感系统及其制备方法和应用，2022-09-30, 中国，202211211770.1（2023-06-公开）CN 116287228 A

[9] 沈薇；宋畅；马紫玉；姜依依；唐盛；刘畅；张景慧，基于液相色谱检测多种MicroRNA自生成可区分荧光探针的一锅法，2022-08-29, 中国，202211039822.1（2023-03-公开）CN 115873948 A

[10] 沈薇；王丽娜；曾学民；唐盛；张景慧；苗紫昀，智能手机APP结合DSN酶微流体芯片比色检测miRNA-21的方法，2022-08-29, 中国，202211039813.2（2023-03-公开）CN 115855920 A

[11] 邝敬宇；陈文慧；李婷婷；沈薇；唐盛；毛威；张景慧；侯伟林，由ATP和H2S协同触发的Ag NPs-DOX-DNA 水凝胶及其制备方法和应用，2022-08-11, 中国，202210962075.2（2023-04-公开）CN 115919744 A

2025年：

[11]Wu Junwen, Zeng Xuemin, Wang, Lina, Zhang Jinghui, Cui Shuhua, Ma Zixiao, Pan Ruirong, Liu Chang, Kong Dezhao, Song Juan, Liu Lei, Feng Chunying, Shen Wei, Suo Xiaocen, Lin Zixia, Lee Hian Kee*, Tang Sheng*, Embedding carbon nanotubes in artificial cells enhances probe transfer, Advanced Materials,  (2025) 2418271 (SCI 一区, IF: 27.4, Top期刊)

[10] Song Meiqi, Zhang Jinghui*, Shen Ke, Hu Yaxue, Shen Wei, Tang Sheng*, Lee Hian Kee*, Application of smart-responsive hydrogels in nucleic acid and nucleic acid-based target sensing: A review , Biosensors and Bioelectronics, 267 (2025) 116803 (SCI 一区, IF: 10.7, Top期刊)

2024年：

[9] Wang Lina, Zhuang Yao, Pan Ruirong, Wang Tingwei, Zhang Jinghui*, Wang Dongyang, Liu Chang, Shen Wei*, Tang Sheng*, Simultaneous targeting and monitoring of free antigen and in-situ membrane antigen in prostate cancer cells via an aggregation-induced emission bifunctional probe, Biosensors and Bioelectronics, 263 (2024) 116581 (SCI 一区, IF: 10.7, Top期刊)

[8] Li Yunxin, Zhang Jinghui*, Chen Jisen, Zhu Feng*, Liu Zhiqiang, Bao Peng, Shen Wei, Tang Sheng*, Detection of SARS-CoV-2 based on artificial intelligence-assisted smartphone: A review, Chinese Chemical Letters,  35 (2024) 109220 (SCI 一区, IF: 9.1, Top期刊)

[7] Ma Ziyu, Xu Junjie, Hou Weilin, Lei Zi, Li Tingting, Shen Wei*, Yu Hui*, Liu Chang, Zhang Jinghui, Tang Sheng*, Single Nucleotide Polymorphisms Detection of Circulating Tumor DNA by Strand Displacement Amplification Coupled with Liquid Chromatography, Analytical Chemistry, 96 (2024) 5195-5204 (SCI 一区, IF: 7.4, Top期刊)

[6] Hou Weilin, Mao Wei, Yu Dasong, Pan Yuquan, Shen Wei*, Zhang Jinghui, Kong Dezhao, Zang Linlin, Dai Hongliang, Yang Fu, Lee Hian Kee*, Tang Sheng*, Photo-crosslinked hydrogel as a sensing platform for sensitive detection of free bilirubin in urine samples , Sensors and Actuators B: Chemical, 411 (2024) 135663 (SCI 一区, IF: 8.4, Top期刊）

[5] Zeng Xuemin, Wang Lina, Liu Chang*, Zhang Jinghui, Shi Hai-Wei, Shen Wei*, Kong Dezhao, Huang Cheng, Lee Hian Kee, Tang Sheng*, An integrated liposome-based microfluidic strategy for rapid colorimetric analysis: A case study of microRNA-21 detection , Talanta, 272 (2024) 125838 (SCI 一区, IF: 6.1, Top期刊)

[4] Song Chang, Ma Ziyu, Zhang Mengyu, Liu Chang*, Tang Sheng*, Zhang Jinghui, Song Juan, Yu Hui, Lee Hian Kee, Shen Wei*, Multiplex detection of single nucleotide polymorphisms by liquid chromatography for non-small cell lung cancer staging, Analytical Chemistry, 96 (2024) 1054-1063 (SCI 一区, IF: 7.4, Top期刊)

2023年：

[3] Chen Wenhui, Li Tingting, Chen Chengbo, Zhang Jinghui, Ma Ziyu, Hou Weilin, Yao Yao, Mao Wei, Liu Chang, Kong Dezhao,Tang Sheng*, Shen Wei*, Three-dimensional ordered DNA network constructed by a biomarker pair for accurate monitoring of colorectal cancer, Biosensors and Bioelectronics, 232 (2023) 115335 (SCI 一区, IF: 12.545, Top期刊）

2022年：

[2] Wang Lina, Zhang Jinghui, Shen Wei*, Zeng Xuemin, Lee Hian Kee*,Tang Sheng*, Can direct-immersion aqueous-aqueous microextraction be achieved when using a single-drop system?Analytical Chemistry, 94 (2022) 12538-12545 (SCI 一区, IF: 8.008, Top期刊)

[1] Yao Yao, Hu Tao, Chai Yaqian, Ju Jiahe, Zhang Jinghui*, Shen Wei*, Shi Haiwei, Liu Chang, Huang Cheng, Tang Sheng*, A rapid cusp-covering to Au nanostar as plasmonic sensor in a single-drop microreactor for the determination of kanamycin in biosamples, Sensors and Actuators B: Chemical, 366 (2022) 131993 (SCI 一区, IF: 7.460, Top期刊）

2021年以前：

[1] Jinghui Zhang, Zongyang Qiu, Jiahui Fan, Fang He, Wenyuan Kang, Sihui Yang, Hong-Hui Wang*, Jing Huang*, Zhou Nie*, Scan and Unlock: A Programmable DNA Molecular Automaton for Cell-Selective Activation of Ligand-Based Signaling. Angewandte Chemie International Edition, 2021, 60(12), 6733-6743.

[2] Shanfang Hu¹, Jinghui Zhang¹, Rui Tang, Jiahui Fan, Huiqiong Liu, Wenyuan Kang, Chunyang Lei, Zhou Nie*, Yan Huang*, Shouzhuo Yao, Click-Type protein-DNA conjugation for Mn²⁺ imaging in living cells. Analytical Chemistry, 2019, 91(15), 10180-10187.

[3] Jinghui Zhang¹, Tai Sun¹, Aping Niu¹, Yu-Mei Tang, Shun Deng, Wei Luo, Qun Xu*, Dapeng Wei*, De-Sheng Pei*, Perturbation effect of reduced graphene oxide quantum dots (rGOQDs) on aryl hydrocarbon receptor (AhR) pathway in zebrafish. Biomaterials. 2017,133, 49-59.  

[4]  Miao Wang, Fang He, Hao Li, Sihui Yang, Jinghui Zhang, Pradipta Ghosh, Hong-Hui Wang*, Zhou Nie*. Near-Infrared Light-Activated DNA-Agonist Nanodevice for Nongenetically and Remotely Controlled Cellular Signaling and Behaviors in Live Animals. Nano Letter, 2019, 10; 19(4), 2603-2613.

[5] Hao Li, Miao Wang, Tianhui Shi, Sihui Yang, Jinghui Zhang, Hong-Hui Wang *, Zhou Nie *. A DNA-Mediated Chemically Induced Dimerization (D-CID) Nanodevice for Nongenetic Receptor Engineering To Control Cell Behavior. Angewandte Chemie International Edition, 2018, 6; 57(32):10226-10230.

[6] Shun Deng, Pan-Pan Jia, Jinghui Zhang, Muhammad Junaid, Aping Niu, Yan-Bo Ma, Ailing Fu*, De-Sheng Pei*, Transcriptomic response and perturbation of toxicity pathways in zebrafish larvae after exposure to graphene quantum dots (GQDs), Journal of Hazardous Materials, 2018, 357, 146-158.

[7] Li Jing¹, Aping Niu¹, Chun-Jiao Lu, Jinghui Zhang, Muhammad Junaid, Phyllis R Strauss, Ping Xiao, Xiao Wang, Yi-Wei Ren*, De-Sheng Pei*. A novel forward osmosis system in landfill leachate treatment for removing polycyclic aromatic hydrocarbons and for direct fertigation. Chemosphere, 2017, 168, 112-121.

[8] Jinghui Zhang¹, Aping Niu¹, Jing Li, Jianwei Fu, Qun Xu*, De-Sheng Pei*. In vivo characterization of hair and skin derived carbon quantum dots with high quantum yield as long-term bioprobes in zebrafish. Scientific Reports, 2016, 6, 37860.

[9] Jianwei Fu, Zhonghui Chen, Minghuan Wang, Shujun Liu, Jinghui Zhang, Jianan Zhang, Runping Han, Qun Xu*. Adsorption of methylene blue by a high-efficiency adsorbent (polydopamine microspheres): Kinetics, isotherm, thermodynamics and mechanism analysis. Chemical Engineering Journal, 2015, 259, 53-61.